| 1811 | Sir Charles Bell | different functions of dorsal and ventral roots of the spinal cord |
| 1812 - 1824 | Legallois | localized respiratory center in the brain |
| Flourens | identified cerebellium as center of coordination | |
| 1826 | Johannes Miller | doctrine of specific nerve energy |
| 1828 - 1831 | John Abacrombie Richard Bright |
specific lesions associated with recognizable physical disorders |
| 1846 | Suggestion that pain mediated by specific pathways |
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