From the Dancing Manias to Sydenham's Chorea - Final Discovery of Etiology

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1899 Wasserman, Wesphal, Malkoff isolated a diplococcus from the pericardial and spinal fluid of a child dead of rheumatic pericarditis and chorea."
1901-1903 Poynton, Paine, and Holmes injected IV diplococci obtained from the fatal cases and produced irregular movements, carditis and arthritis.