
Initially, the clinician generates several hypotheses based on patterns of symptoms. Subsequent questions are directed to support or modify these hypotheses. An experienced clinician may go through the hypothesis generation and evaluation loop several times during the course of an interview.


| Abdominal Pain | |||||||
|---|---|---|---|---|---|---|---|
| Location | Quality | Radiation | Timing | Worse | Better | Other | |
| Appendicitis | periumbilical, then RLQ | crampy early, steady late | 4-6 hour onset | movement late | anorexia, nausea, low grade fever | ||
| Cholecystitis | RUQ | steady ache | right scapula | gradual onset | movement, deep breath | anorexia, nausea, vomiting, fever | |
| Renal Stone | flank | crampy, severe | groin on same side | sudden onset | vomiting, urinary symptoms, blood in urine | ||
| Gastroenteritis | variable | crampy | moves around | 4-6 hour onset | food | nausea, vomiting, diarrhea. fever | |
| Peptic Ulcer | epigastric | gnawing, burning, pressure | back | intermittent | food, antacids | nausea, vomiting, bloating, heartburn | |
| Pancreatitis | epigastric | variable | back | variable | lying down | bending forward | nausea, vomiting, fever |
| Obstruction | variable | crampy | paroxysmal | vomiting bile (high), obstipation | |||
| Chest Pain | |||||||
|---|---|---|---|---|---|---|---|
| Location | Quality | Radiation | Timing | Worse | Better | Other | |
| Angina Pectoris | retrosternal | pressure | arms, neck, jaw | 1-10 minutes | exertion | rest, NTG | SOB, nausea, sweats |
| Myocardial Infarction | retrosternal | pressure | arms, neck, jaw | 20 min - few hours | SOB, nausea, vomiting, sweats, weakness | ||
| Dissecting Aneurusm | anterior chest | tearing | neck, back, abdomen | abrupt onset, persistent | |||
| Pleuritis | variable | sharp | variable | breathing, coughing | holding/lying on side | ||
| Espophagitis/Spasm | retrosternal | burning, pressure | arms, neck, jaw, back | variable | eating, drinking, lying | antacids, NTG | regurgitation, dysphagia |
| Chest Wall Pain | variable | sharp or dull ache | hours to days | movement | local tenderness | ||
| Headache | |||||||
|---|---|---|---|---|---|---|---|
| Location | Quality | Onset | Duration | Worse | Better | Other | |
| Tension | bilateral, front or back | ache or pressure | gradual | hours - days | driving, typing | relaxation | anxiety or depression, neck pain |
| Migraine | uni or bilateral | throbbing | rapid | hours - days | alcohol, food, noise | quiet, dark, sleep | nausea, vomiting, visual prodrome |
| Cluster | unilateral behind eye | steady, severe | abrupt | 1-2 hours | alcohol | runny nose, tearing on same side | |
| Sinusitis | cheek or eye | ache or pressure | gradual | daily | coughing | decongestants | nasal discharge, fever, local tenderness |
| Arteritis | over temporal artery | ache or throb | variable | week - months | fever, local tenderness | ||
| Meningitis | generalized | variable, severe | rapid | variable | fever, stiff neck | ||
| Tumor | variable | steady ache | variable | progressive | coughing, straining | nausea, vomiting, neurologic problems | |