Hemophilia A

Decreased FVIII activity

Prolonged aPTT, but corrects with 1:1 mixture with normal plasma

Normal or slightly prolonged aPT

Normal bleeding time

Normal thrombin time

Factor VIII inhibitor

Decreased FVIII activity

Prolonged aPTT which does not correct with 1:1 mixture with normal plasma

Normal or slightly prolonged aPT

Normal bleeding time

Normal thrombin time