Answer

Bumps

Condyloma Acuminata

(Papillomavirus-6 and Papillomavirus-11)

A 22 year old female presents to her gynecologist complaining of genital "bumps." She admits to being sexual active although she states that she only has one partner. Physical exam reveals brown, warty lesions.

Labs: Presence of koilocytes in the squamous epithelial cells.

Discussion: The diagnosis of genital warts is made by clinical presentation. Genital warts, also called condylomata acuminata are caused primarily by HPV-6 and HPV-11. When the papillomaviruses infect the cells, they produce a cytoplasmic vacuole. This process is called koilocytosis. The presences of koilocytes indicate an infection by HPV. Transmission occurs by sexual contact. This patient was infected by her partner.

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