Small Bowel Bacterial Overgrowth (SBBO)

Table 6. Tests for SBBO
Tests
Simplicity
Sensitivity
Specificity
Safety
Culture Poor Excellent Excellent Good
Urinary Indican Good Poor Poor

Excellent

Jejunal Fatty Acids Poor Fair Excellent Good
Jejunal Bile Acids Poor Fair Excellent Good
Fasting Breath H2 Excellent Poor Excellent Excellent
C-bile Acid BT Excellent Fair Fair Good
C-xylose BT Excellent Excellent Excellent Good
Lactulose-H2 BT Excellent Fair Fair Excellent
Glucose-H2 BT Excellent Good Fair Excellent

Table 7. Effective Antimicrobial Agents for Treating SBBO
Agent
Dose (10-day course)

1. Tetracycline

250mg four times/day
2. Doxycyline 100mg twice/day
3. Minocycline 100mg twice/day

4. Amoxicillin - Clavulanic acid

850mg twice/day
5. Cephalexin + Mitronidazole 250mg four times/day

6. Colistin +

Metronidazole

250,000 IU/kg/day

250mg three time/day

7. Trimethroprim - Sulfamethoxazole One DS tab twice/day
8. Chloramphenical 250mg four times/day
9. Ciprofloxicin 500mg twice/day
10. Norfloxacin 400mg twice/day

 

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