|
Small
Bowel Bacterial Overgrowth (SBBO)
|
| Table 6. Tests for SBBO | ||||
|
Tests
|
Simplicity
|
Sensitivity
|
Specificity
|
Safety
|
| Culture | Poor | Excellent | Excellent | Good |
| Urinary Indican | Good | Poor | Poor |
Excellent |
| Jejunal Fatty Acids | Poor | Fair | Excellent | Good |
| Jejunal Bile Acids | Poor | Fair | Excellent | Good |
| Fasting Breath H2 | Excellent | Poor | Excellent | Excellent |
| Excellent | Fair | Fair | Good | |
| Excellent | Excellent | Excellent | Good | |
| Lactulose-H2 BT | Excellent | Fair | Fair | Excellent |
| Glucose-H2 BT | Excellent | Good | Fair | Excellent |
| Table 7. Effective Antimicrobial Agents for Treating SBBO | |
|
Agent
|
Dose (10-day course)
|
|
1. Tetracycline |
250mg four times/day |
| 2. Doxycyline | 100mg twice/day |
| 3. Minocycline | 100mg twice/day |
|
4. Amoxicillin - Clavulanic acid |
850mg twice/day |
| 5. Cephalexin + Mitronidazole | 250mg four times/day |
|
6. Colistin +
|
250,000 IU/kg/day 250mg three time/day |
| 7. Trimethroprim - Sulfamethoxazole | One DS tab twice/day |
| 8. Chloramphenical | 250mg four times/day |
| 9. Ciprofloxicin | 500mg twice/day |
| 10. Norfloxacin | 400mg twice/day |
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